OYO Inn & Suites Medical Center San Antonio

2-star hotel Good 3782 NW Loop 410, San Antonio, TX, 78229
OYO Inn & Suites Medical Center San Antonio

About OYO Inn & Suites Medical Center San Antonio

Conveniently set in the South Texas Medical Center district of San Antonio, OYO Inn & Suites Medical Center San Antonio is located 8 miles from The Alamo, 8.1 miles from Ripleys Believe It Or Not Museum and 8.2 miles from Henry B. Gonzalez Convention Center. The 3-star hotel has air-conditioned rooms with a private bathroom and free WiFi. The Shops at La Cantera is 10 miles away and Six Flags Fiesta Texas is 11 miles from the hotel. At the hotel, every room comes with a desk. Guest rooms in OYO Inn & Suites Medical Center San Antonio are equipped with a TV and free toiletries. Speaking English and Spanish, staff will be happy to provide guests with practical guidance on the area at the reception. Alamodome is 8.8 miles from the accommodation, while Tower of the Americas is 9.1 miles away. San Antonio International Airport is 6.2 miles from the property.

Amenities

  • 24-hour front desk
  • On-site dining
  • In-room refrigerator
  • In-room microwave
  • Smoke-free property
  • Air conditioning
  • Elevator

Reviews

3.4 / 5

The hotel reviews are mixed, with guests praising the friendly staff and quick check-in, while criticizing the cleanliness and maintenance of the rooms. The location and affordability are also mentioned as positives, but the condition of the hotel's exterior and grounds are noted as negatives.

What guests liked
  • Friendly staff
  • Affordable pricing
What could be better
  • Cleanliness issues
  • Poor maintenance and upkeep
  • Melanie Jun 2026 · via hotels.com
    5/5

    great place to stay close to the hospital. Would stay there again

  • Ronnie Jun 2026 · via expedia
    5/5

    It was quiet and clean and the staff was very friendly

  • Mekana May 2026 · via expedia
    1/5

    There was a mattress outside our room for the whole stay. And it’s not clean

  • Cecilia May 2026 · via priceline
    5/5

    It was near the hospital so we could b near our loved one . Also it was near restaurants . ☺️ Not apply

  • Cecilia May 2026 · via booking
    5/5

    It was near the hospital so we could b near our loved one . Also it was near restaurants . ☺️ Not apply

  • Tony May 2026 · via booking
    5/5

    Exceptional

  • Melissa Apr 2026 · via booking
    5/5

    I liked the check in process from front desk smooth , easy to understand and a short process N/A

  • Melissa Apr 2026 · via priceline
    5/5

    N/A

  • Laura Apr 2026 · via expedia
    5/5

    Very clean, respectful staff hotel room was very beautiful cleaned most definitely will be returning

  • Tonya Apr 2026 · via expedia
    4/5

    I appropriated their accommodation to give us a bottom floor room (back problems)

  • Daniel Apr 2026 · via booking
    5/5

    Exceptional

  • Ashley Mar 2026 · via booking
    3/5

    Pleasant

  • Kendy Mar 2026 · via booking
    5/5

    Exceptional

  • Noel Mar 2026 · via booking
    4/5

    Very good

  • Rodriquez Mar 2026 · via booking
    0.5/5

    Bad

  • Barbara Feb 2026 · via booking
    3/5

    Pleasant

  • Egger Jan 2026 · via booking
    5/5

    Exceptional

  • Thomas Dec 2025 · via expedia
    4/5

    Staff was courteous and professional and the room is nice.

  • Thomas Dec 2025 · via expedia
    4/5

    The staff was courteous, and professional and the room was very good.

  • Archie Dec 2025 · via hotels.com
    5/5

    Excellent property!! Staff were very kind.

  • Alexander Nov 2025 · via expedia
    1/5

    Checked in Nov. 8th 2025. Current date Nov. 25th 2025. Does not take this long for a refund. If there were any damges ( which there was not) I have not been given a bill explaining that. I have filed a dispute with my Credit Card company. Hopefully they can get me my deposit back.

  • Loami Nov 2025 · via booking
    1/5

    comfortable beds water from 2nd floor filters to 1st floor. had to shower very carefully to not spill any water on the floor. lock didn’t worked properly, we struggled opening the door. a lot of noise outside we couldn’t rest. called front desk no answer.

  • Loami Nov 2025 · via priceline
    1/5

    comfortable beds water from 2nd floor filters to 1st floor. had to shower very carefully to not spill any water on the floor. lock didn’t worked properly, we struggled opening the door. a lot of noise outside we couldn’t rest. called front desk no answer.

  • Carlos Nov 2025 · via expedia
    5/5

    Staff was friendly and helpful, with no issues checking-in.

  • raul Oct 2025 · via expedia
    2/5

    The pics in the web page are extremely deceiving.

  • Everett Oct 2025 · via booking
    4/5

    It was clean and right on the highway, so it was very convenient

  • Everett Oct 2025 · via priceline
    4/5

    It was clean and right on the highway, so it was very convenient

  • Juan Sep 2025 · via expedia
    5/5

    Always great stay

  • Olga Aug 2025 · via hotels.com
    5/5

    The location is great the staff were very nice the room was very agreeable thanks

  • Joshua Jul 2025 · via hotels.com
    4/5

    It’s was perfectly in the middle of what we come for.

  • Olga Jun 2025 · via hotels.com
    5/5

    Was good last minute trip thanks

  • Anonymous Jun 2025 · via priceline
    1.5/5

    The smell in the room was unbearable

  • Robert May 2025 · via expedia
    5/5

    Quiet area

  • Magaly Apr 2025 · via priceline
    1/5

    No good towels and smells no good

  • Magaly Apr 2025 · via booking
    1/5

    No good towels and smells no good

  • Anonymous Apr 2025 · via priceline
    3.5/5

    no coffee in room

  • Stewart Apr 2025 · via hotels.com
    1/5

    AC unit is a thru wall unit so bed next to window was freezing while other bed was hot. Will not be staying there again.

  • Deepak Mar 2025 · via hotels.com
    1/5

    Smelly, carpet sticky and dirty, sheets with stains. Blanket with holes.

  • Wilfredo Mar 2025 · via expedia
    5/5

    This is a beautiful place to stay ❤️ 💖

  • Wilfredo Mar 2025 · via expedia
    5/5

    This is a beautiful place to stay lovely 😍

  • Wilfredo Feb 2025 · via expedia
    5/5

    I love this place lovely

  • Justin Feb 2025 · via expedia
    3/5

    It was ok guy at front desk rude

  • Wilfredo Feb 2025 · via expedia
    5/5

    Nice place to stay lovely

  • edward Feb 2025 · via expedia
    3/5

    Liked location. Did not like room

  • Wilfredo Feb 2025 · via expedia
    5/5

    Beautiful place to stay love it

  • James Nov 2024 · via hotels.com
    3/5

    Old, dated facility.

  • Jesse Oct 2024 · via hotels.com
    5/5

    It was comfortable

  • Buffy Oct 2024 · via expedia
    5/5

    Was a great little place

  • Rodolfo Sep 2024 · via expedia
    1/5

    I stayed 5 total nights not even once the room was cleaned or bed made not even one time

  • Adam Aug 2024 · via expedia
    5/5

    Good

  • Alfred Jul 2024 · via expedia
    5/5

    Greatest

  • hong Jul 2024 · via expedia
    2/5

    The towel was yellow and worn out. Looks bad

  • Jose Mar 2024 · via expedia
    1/5

    Nasty

  • Verified Mar 2024 · via hotels.com
    3/5

    parking is random, limited, sketchy neighborhood area, faces trash area of restaurant in front of location

  • Kenneth Mar 2024 · via expedia
    3/5

    1. The staff was friendly 2. Was a quick check-in 3. The water was hot 4. The bed & pillows were comfort 5. TV, fridge, microwave worked 6. Ice maker worked. Negative was the towels had stains on them,we had to ask for clean ones. The shower curtain had stains on them as well. The toilet seat was not secure. Needed fixing. The grounds need cleaning, the doors have pealing paint as well the rest of the building and stairs need paint. The cost per room was very cheap so I guess you get what you pay for. If your staying a night in San Antonio and on a budget, this place would be fine for you. Next time for me I will pay more for more cleanliness elsewhere.

  • Karen Feb 2024 · via expedia
    3/5

    Area appeared safe off 410. Room was so so. Holes in bedspread, holes in curtain. Cracks in granite sink. My drink froze in fridge overnite.teied to thaw in microwave, but then it was too watery. Tub had what appeared to be cigarette burns on edge. But major problem was that the towels and washcloths were dingy and not fluffy. Past Time to replace these!!

  • Santos Dec 2023 · via hotels.com
    5/5

    My husband and son had a great stay it was close to the UT HOSPITAL so it was great for my family to come see me during my stay. The floor was a little dingy but it's expected with an older hotel.

  • Chasity Nov 2023 · via hotels.com
    1/5

    Absolutely awful! Didn’t stay!! Tried 2 different rooms and both equally disgusting! Pubs on bed sheets! Roach poop everywhere! Smell was gross! Dirty towels on floor! Dead flies! Bugs!!! On wall!!

  • Amanda Oct 2023 · via expedia
    5/5

    Was simple clean reasonably price and close to my destination

  • Robert Oct 2023 · via expedia
    5/5

    Quite and comfortable

  • Robert Oct 2023 · via expedia
    5/5

    Safe quite easily accessible

  • Jilaine Sep 2023 · via expedia
    5/5

    The gentleman at front was pleasant, caring, friendly. Rooms clean! Great experience will return when in area

  • Adam Sep 2023 · via expedia
    2/5

    Dirty

  • Lydia Jul 2023 · via hotels.com
    1/5

    Room was filthy, sticky and smelly..stayed 1 of 2 nights and checked into another hotel next morning.

  • Claudia Jul 2023 · via expedia
    2/5

    I WOULD NOT RECOMMEND THIS PLACE DID NOT HAVE A GOOD SLEEP. FELT LIKE SOMONE WAS LOOKING AT ME.

  • Carol Jul 2023 · via expedia
    5/5

    The staff here at this location was heart-warmin and very inviting. The lady at the front office was wonderful. Conversation was open and very attentive. This location had a nice swimming pool. The guests on this weekend were all nice and friendly. I am a pet lover, so i liked the dogs...

  • Brett Mar 2023 · via expedia
    5/5

    Not bad for the price. Everything worked, clean, comfortable, easy check-in/check-out.

  • Dustin Feb 2023 · via hotels.com
    5/5

    Clean hotel. Great staff and great local restaurants close by. Couldn’t be happier with my stay here. Felt safe even at night. Impressive. Very good experience.

  • Peter Feb 2023 · via hotels.com
    2/5

    Very disappointing barely a 2 star. Check in thru security window in lobby. Asked if parking was safe and guy went full lawyer. Room old and worn but at least clean. Would not have brought family.

  • Cynthia Jan 2023 · via hotels.com
    5/5

    It was a wonderful stay.

  • Wilfredo Nov 2022 · via expedia
    5/5

    I like the place is very comfortable and easy to park I have a medium trunk that the parking is very comfortable 👌

  • Gloria Oct 2022 · via expedia
    1/5

    The room was nasty smelly dirty

  • Nick Sep 2022 · via expedia
    5/5

    Just booked myself another 2 day getaway and this place is amazing. The manager, could honestly not be anything but the nicest gentleman I’ve encountered with hotel stays. Cleanest property, friendliest, quiet, highway accessible, don’t let the location (visually) fool you, this is a diamond in the rough so better book it before it becomes anymore popular and you can’t. 5 stars

  • Donna Aug 2022 · via hotels.com
    1/5

    First, went to room to get AC going. The unit was so loud but decided I could cope with it for one night since I wasn't going to spend much time in room. The carpet loomed like it hadn't been vacuumed forever - I travel with slippers so I could cope. Headed out for some time with friends. Arrived back in room ready for some sleep. When i pulled back the sheet/bedspread, the sheets were FILTHY!! It looked like someone had slept there and then made the bed. That was the final straw! So just after midnight, I packed everything back in the car, checked out (when I told clerk about condition of room, his response was "ok") and drove the over 3 hours home. DON'T STAY HERE!

  • Shanika Jul 2022 · via expedia
    2/5

    Staff was rude and took photo copy of debit card. Made me feel unsafe with that and didn’t provide explanation when asked. Was rude when asked why a copy of debit card was taken.

  • Jose Jul 2022 · via expedia
    3/5

    I knew what I was getting for the price…. But you can really work in being a bit more clean …. Other then that not bad…..

  • ingrid Jun 2022 · via expedia
    4/5

    Good

  • Josh Jun 2022 · via hotels.com
    3/5

    The hotel had a decent location, the only two things I didn't like was the bed was right next to the ac machine and the table was close to the bathroom. Every other hotel it is reversed. Everytime the ac would kick in, I would wake up. The other issue was the bed only had two small pillows. It would help a lot if you could put one or two more on the beds.

  • Marlis Jun 2022 · via hotels.com
    3/5

    The service male was nice, but only came to the open window. The lobby was closed. I prepaid, yet he wanted $80 cash. I only had a ctedit card, which he took out of my view - which I do not like. (fraud can happen) The room had a bad body odor or mildew odor and felt damp. The bathroom and bed sheets were clean, but the carpet seemed old & damp. a 2nd or thicker blanket could be better - as it got cold even with the air cond higher. Towels were clean, but worn. TV had good choices. The frig and microwave are helpful.

  • Marcellus May 2022 · via expedia
    1/5

    This has been the WORST hotel Ive ever stayed in. It wasnt properly cleaned. There was a burrito left in the microwave from the previous stay. I had dirty towels in the room and the tub was FILTHY. Dont waste your money

  • William Mar 2022 · via hotels.com
    4/5

    Thanks for everything.

  • Linda Feb 2022 · via expedia
    3/5

    Very average 2 star facility that meets minimum standards. Quick check-in and plenty of close-in parking

  • Rose Dec 2021 · via expedia
    5/5

    It was only about 15 minutes from riverwalk

  • Jenni Dec 2021 · via expedia
    2/5

    You get what you pay for, I guess.

  • Ruth Oct 2021 · via hotels.com
    2/5

    The bath tub was filthy, full of grease and grim and the shower curtain had mold on it. I will not be staying on this property anymore. No coffee maker. This is a motel, rooms accessed from outside.

  • Roseann Oct 2021 · via expedia
    1/5

    We did not like the fact that their was mold in the bathroom and the vent in the restroom you could see right thru it. There was also hair on bed like sheets and blankywere never chnaged and their was also stains on the sheets and blankets also like the carpet was dirty like it was also not vacuumed. We will never stay at that hotel again it was not worth the amoumt of money we paid for 168 or something likw for the days we were there

  • Jose Oct 2021 · via expedia
    4/5

    Good location . big room

  • Verified Aug 2021 · via expedia
    1/5

    They took all money that they can. Just be careful on their procedure

  • Verified Jul 2021 · via expedia
    1/5

    Room was disgusting.

  • Donald Jul 2021 · via hotels.com
    2/5

    Not so good. This is an OLD motel taken over by this new company. Very dumpy and in disrepair, although the bed was comfy. My wife thought that it was dirty.They didn't even have COFFEE!

  • Verified May 2021 · via expedia
    2/5

    I had never give a bad review but for a 100.00 bucks room the area was scary and the room no way. The only good was it UBS charge connection for my phone. Expedia you are loosing credibility with this kind of places.

  • Verified May 2021 · via expedia
    4/5

    It’s laid back

  • Verified Apr 2021 · via expedia
    1/5

    With the reviews this place had I thought it would be be a nice hotel but it was terrible.

  • Verified Apr 2021 · via expedia
    2/5

    Towels were replaced with what seemed like dirty towels. Bed was not made. Carpet was very dirty. Bed was comfortable which made stay tolerable.

  • Verified Mar 2021 · via hotels.com
    1/5

    The front desk staff was very rude and I want to say prejudice. The room was originally reserved in my boyfriend’s name and he did not realize his ID had expired until he tried to check in. So I asked if the reservation could be switched over to my name and he told me he could not rent me the room if my boyfriend was staying with me cause his ID had expired. I have never in my life heard of such thing! I would not recommend this motel to anyone!

  • Verified Mar 2021 · via expedia
    4/5

    Helpful staff and cleanliness. The place seems old, but it is clean so that makes up for that.

  • Verified Sep 2020 · via hotels.com
    4/5

    Room was clean and tidy. Ac works great.

  • Michele Jun 2020 · via expedia
    5/5

    Great room and great price! Friendly staff and clean rooms.

  • JoeyD Jun 2020 · via expedia
    5/5

    Great price for a spot if your in need. Staff was friendly and it was in a decent spot alot of restaurants and stores all around.

  • Itsme Mar 2020 · via expedia
    2/5

    It was very dusty and there was some nasty splatter of brownish/reddish paint (I hope it was paint) on bathroom door and door frame. The blow dryer holder had a lot of dust accumulated and so did the lamps. The beds didn’t smell or look clean😑

  • Verified Mar 2020 · via expedia
    5/5

    Was a great stay. Great staff and quiet rooms. The location is quiteconvenient

  • Verified Mar 2020 · via expedia
    5/5

    The price is really good and the staff very friendly!!!!

  • Verified Mar 2020 · via expedia
    5/5

    This property provided a quiet stay and the staff were helpful.

  • Rita Feb 2020 · via hotels.com
    5/5

    The room was very comfortable and the mattress bed was excellent. First night my husband and I have slept so comfortably. ll amenities were in the room as described on website. We will book again on next stay in San Antonio, TX.

  • Mary Feb 2020 · via hotels.com
    5/5

    Great service. Very comfortable very clean and there is a really good Mexican restaurant in front of the hotel Called Jalisco. A mall right across from the hotel easy access to the highway.

  • AngieF-Sauceda Jan 2020 · via expedia
    5/5

    The clerk was very friendly. He recommend places to eat. There were plenty off towels. We would recommend them.

Frequently asked questions about OYO Inn & Suites Medical Center San Antonio

Does OYO Inn & Suites Medical Center San Antonio have free Wi-Fi?
Yes, OYO Inn & Suites Medical Center San Antonio offers free Wi-Fi for all guests.
Does OYO Inn & Suites Medical Center San Antonio offer parking?
Yes, OYO Inn & Suites Medical Center San Antonio offers free parking on-site.
Does OYO Inn & Suites Medical Center San Antonio have meeting spaces, conference centers, or conference rooms?
OYO Inn & Suites Medical Center San Antonio does not list dedicated meeting or conference facilities. For business event venues in San Antonio, see business hotels in San Antonio.
Does OYO Inn & Suites Medical Center San Antonio have a fitness center?
OYO Inn & Suites Medical Center San Antonio does not list an on-site fitness center. Some properties partner with nearby gyms — check directly with the hotel.
Where is OYO Inn & Suites Medical Center San Antonio located, and how walkable is the area?
OYO Inn & Suites Medical Center San Antonio is located at 3782 NW Loop 410, San Antonio, TX 78229. With a Walk Score of 55, the area is rated Somewhat Walkable. Some errands can be done on foot, but a car or rideshare is helpful for most trips.

House rules

Check in 3:00 PM
Check out 11:00 AM
Cancellation Not available
Children Not available